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Scientists stumble upon potential new cure for baldness

Scientists stumble upon potential new cure for baldness

WAY-316606, the new compound, marks a protein that is recognized to stop the growth of the hair.

British scientists identified a drug, originally designed as a treatment for osteoporosis, that could treat human hair loss.

Now, there are two hair loss drugs available, the finasteride and minoxidil, which have a mixed reviews and results.

There are only two drugs now on the market that claim to treat male-pattern balding (androgenetic alopecia) - however both have known side-effects and often produce disappointing results.

"When the hair growth-promoting effects of CsA were previously studied in mice, a very different molecular mechanism of action was suggested", Dr. Hawkshaw said in a statement.

While Cyclosporine A (CsA) is usually used to treat autoimmune diseases and suppress transplant rejection, the research team discovered that CsA inhibits a protein which usually restricts the growth of hair follicles.

Then, Nathan Hawkshaw, a research Associate at The University of Manchester, and his colleague found that a compound originally developed to treat osteoporosis, called WAY-316606, targeted the same mechanism as CsA by specifically antagonising SFRP1.

The osteroporosis drug - known as WAY-316606 - stimulated follicles to sprout growing hairs by targeting a protein that plays a key role in baldness.

Day, who was not involved in the study, said she's seen "many strides" in hair loss research over the past decade with research focused on both the immune system and genetics.

The research has been published in the Public Library of Science Biology. These two drugs also have some side effects which include erectile dysfunction, further hair loss and allergic reactions. "For that reason, new treatments are exciting as they give people more treatment options that may be effective".

If applied as a shampoo, scientists found the treatment promotes hair growth.

To try to develop new strategies to promote human hair growth, researchers from the University of Manchester's Center for Dermatology Research conducted lab tests with samples containing scalp hair follicles from more than 40 male hair-transplant patients. The only other alternative open to individuals facing hair loss is transplantation process.

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